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Is Fever Normal After Dialysis? What Can A Patient Expect After A Dialysis


Infection is the most common cause of fever in hemodialysis patients, with malignancy and autoimmune disorders being less common.

That's why a lot of patients undergoing dialysis as part of their health and well-being maintenance are asking: is fever normal after dialysis?

Sometimes, despite empirical treatment, fever persists, and investigations into the aforementioned diagnoses fail to reveal the cause.

Thus, rarer etiologies must be considered, which may appear rather unexpected, especially in patients who have been under medical supervision for a long time.

Renal failure patients are vulnerable to infection.

COPYRIGHT_WI: Published on https://washingtonindependent.com/ebv/is-fever-normal-after-dialysis/ by Rian Mcconnell on 2022-08-17T12:53:56.915Z

Prior to dialysis, 60% of patients with chronic renal failure who required hospitalization were infected, and 39% died from infectious causes.

It was assumed that the uremic state's debility increased the risk of infection and that reversing uremia would reduce the risk of infection.

The recommendation of chronic hemodialysis to lower the uremic state, however, only changed the paradigm and did not, regrettably, address the infection issue.

Dialysis adds new complications to patients who are already suffering from underlying multi-system disease and poor wound healing.

Diabetes mellitus is the leading cause of end-stage renal disease (ESRD), accounting for one-half of all cases, followed by hypertension and chronic glomerulonephritis.

40% of patients have heart disease, and 15% have peripheral vascular disease.

Problems with the intravascular connection, white blood cell and complement dysfunction from contact with dialysis membranes, and exposure to bacteria and pyrogens from contaminated dialysis solutions or inadequately cleaned dialysis machines, in addition to the infection risk associated with frailty and disability, are all issues to consider.

What Is Dialysis?

A patient hooked up to a dialysis machine
A patient hooked up to a dialysis machine

A treatment for those whose kidneys are failing is dialysis.

Your kidneys do not properly filter blood when you have renal failure.

Wastes and poisons accumulate in your bloodstream as a result.

Your kidneys' job of eliminating waste and extra fluid from the blood is performed by dialysis.

Who Needs Dialysis?

Dialysis may be required for people who have kidney failure, also known as end-stage renal disease (ESRD).

Kidney disease can be caused by injuries and conditions such as high blood pressure, diabetes, and lupus.

Some people develop kidney problems for no known reason.

Kidney failure can be a chronic condition or it can occur suddenly (acutely) as a result of a severe illness or injury.

This type of kidney failure may resolve on its own as you recover.

Kidney disease progresses through five stages.

Healthcare providers consider stage 5 kidney disease to be end-stage renal disease (ESRD) or kidney failure.

At this point, the kidneys are performing 10% to 15% of their normal function.

To stay alive, you may require dialysis or a kidney transplant.

While waiting for a transplant, some people receive dialysis.

Types Of Dialysis

Female patient hooked up to a dialysis machine
Female patient hooked up to a dialysis machine

There are 2 types of dialysis. These are:

  • Hemodialysis
  • Peritoneal dialysis


A machine removes blood from your body, filters it through a dialyzer (artificial kidney), and returns the cleaned blood to your body with hemodialysis.

This 3 to 5-hour procedure may be performed three times per week in a hospital or dialysis center.

Hemodialysis can also be performed at home.

It's possible that you'll require shorter sessions of at-home therapy four to seven times per week.

You can do home hemodialysis at night while sleeping.

Peritoneal Dialysis

Through the use of microscopic blood arteries located inside the peritoneum, which lines the inside of the abdominal cavity, peritoneal dialysis filters blood.

This mixture of water, salt, and additional ingredients is a kind of cleansing liquid.

Home is where peritoneal dialysis is performed.

Two approaches can be used for this treatment:

  • Automated peritoneal dialysis uses a machine called a cycler.
  • Continuous ambulatory peritoneal dialysis (CAPD) takes place manually.

What Is The Prognosis For A Person Undergoing Dialysis?

Dialysis patients have been known to survive for up to two decades.

Prospects change with age, general health, the underlying cause of renal failure, and other variables.

The use of dialysis can be discontinued when a kidney transplant has been successful.

Are There Any Activity Restrictions During Dialysis?

Male patient sitting in a big chair with blanket while hooked up to a dialysis machine
Male patient sitting in a big chair with blanket while hooked up to a dialysis machine

Numerous dialysis patients nevertheless lead busy lives, working, raising families, and taking vacations.

When you move, your healthcare practitioner can assist in making arrangements for you to get dialysis at a facility there.

You can bring dialysis solution bags and a portable home dialysis machine with you if you're performing any sort of self-dialysis.

When the abdomen fills with the dialysis solution, those who undergo peritoneal dialysis may need to restrict their physical activity or exercise.

Otherwise, exercise is usually safe for those who are receiving dialysis.

When it comes to taking part in particular sports or activities, you should consult your provider.

When To Call A Doctor

If you have any of these symptoms, you should seek medical attention immediately.

  • Urinating is difficult.
  • Low blood pressure symptoms include dizziness, fainting, unusual thirst (dehydration), and other symptoms.
  • Vomiting and nausea
  • Infection symptoms include fever, oozing, and redness at the AV fistula or catheter site.
  • Abdominal pain that is unbearable.
  • Unusual abdominal or groin bulge (hernia)

Hemodialysis Fever And Antibiotic Administration

Only during dialysis should a fever be evaluated.

Fever and bacteremia during hemodialysis may be the first symptoms of an indolent vascular access infection.

Any hemodialysis patient who has a fever should have blood cultures drawn.

A profound neutropenia and the sudden high flow through a colonized vascular access device are two events that occur during the initial period of hemodialysis and may play a role in this presentation.

Fever and bacteremia could also be caused by hemodialysis machines.

Waterborne organisms can contaminate the blood in a variety of ways, including a leak in the system, contamination of the water source, rapid growth of bacteria in dialysate, or colonization of the patient through contact contamination.

Consider a sterility break if cultures show Burkholderia cepacia, Stenotrophomonas maltophilia, Pseudomonas stutzeri, Pseudomonas aeruginosa, or Aeromonas sp.

Fever caused by endotoxin absorption, interleukin activation, or leukocyte pyrogen from the dialysis coil may be non-infectious.

For hemodialysis-related fever, empiric antibiotic therapy should be started.

Doctors always prescribe antibiotics at the end of a dialysis session, which last until the next session.

This post-dialysis approach is straightforward, ensures compliance, encourages outpatient treatment, and is inexpensive.

In the absence of methicillin resistance, cefazolin has been our go-to antibiotic for gram-positive bacterial infections.

For gram-negative bacterial infections, cefoxitin, ceftazidime, and aminoglycosides can also be dosed in this manner (Table 2).

Doctors do not use vancomycin unless the patient is septic or has a previously documented MRSA infection in order to limit the spread of vancomycin-resistant gram-positive bacteria.

Instead, they give 1.5 grams of cefazolin and 120 mg of gentamicin until the culture results come in.

In critically ill patients, continuous replacement renal therapy, also known as CVVH (Continuous Venovenous Hemofiltration) or CVVHD (Continuous Venovenous Hemodialysis), is commonly used.

Because the clearance of most molecules, including creatinine, resembles that of a functioning kidney, antibiotic dosing differs from that of intermittent hemodialysis.

Another approach is to use serum antibiotic concentrations, creatinine levels, and published nomograms for dosing in renal insufficiency as a guide.

Infection Control

When it comes to lowering healthcare expenditures, keeping patients out of the hospital, and enhancing their quality of life, infection prevention is one of the few options.

Most infections in ESRD patients are caused by common pyogenic bacteria found naturally in the patient's endogenous flora.

Patients with end-stage renal illness may have an S. aureus carriage rate of up to 70%.

More than half of all infections are related to vascular access, with S. aureus on the skin being the most prevalent pathogen.

Patients with a history of bacteremia are at a higher risk of developing the infection again, suggesting they may be chronic staphylococcus carriers.

Nasal mupirocin treatment dramatically decreases both the prevalence of carriage and the incidence of eventual bacteremia.

Clinical evidence suggests that mupirocin resistance will emerge if the antibiotic is used extensively.

Limiting mupirocin prophylaxis to exclusively S. aureus carriers may prove more effective than the current protocol.

Patients with poor dialysis, malnutrition, or cleanliness have a higher risk of developing a vascular access infection.

The most vulnerable vascular access is a venous catheter(VC).

Without a strategy for a more secure VAD, they should be avoided.

More than 40% of dialysis patients die, and 25% of patients account for almost half of the overall cost of care.

We have created an indicator to stratify patient risk for future infection using information about vascular access, previous infection history, co-morbidity indices, and physical activity scales.

To shift the status quo, we're investing heavily in preventative home services for this vulnerable population of patients with chronic conditions.

People Also Ask

How Will I Feel After Dialysis?

How Do You Treat Fever And Chills During Hemodialysis?

Empirical broad-spectrum antibiotics are frequently used, and the prevalence of infection among hemodialysis patients who report chills is not well understood.

Why Do I Feel Sick After Dialysis?

Low blood pressure, which can happen when too much fluid is withdrawn from the circulation during treatment, is the most typical side effect of hemodialysis.

As a result, the pressure decreases, resulting in nausea and vertigo.

Why Do Dialysis Patients Get Chills?

During dialysis, patients who complained of chills had significant rates of infection and bacteremia.

These high rates of infection justify the widespread practice of giving hemodialysis patients who report with chills an immediate empirical antibiotic therapy.

How Do Dialysis Patients Prevent Chills?

High rates of infection (60%) are prevalent in hemodialysis patients who experience chills during dialysis, whether or whether they have a temperature.

Patients who present without fever, leukocytosis, or hypoalbuminemia, have no evident infection source, fistula or graft access, and are at minimal risk for bacteremia may be examined without receiving immediate antibiotic treatment.

Following a chills episode, antibiotics should be administered to all other patients.


People who have kidney failure or end-stage renal disease are candidates for the life-saving treatment known as dialysis (ESRD).

You could continue to get dialysis treatment indefinitely or only until you are able to receive a kidney transplant.

There are numerous approaches to dialysis to choose from.

Others would rather go to a hospital or a dialysis clinic for their treatment, while others opt to perform their dialysis treatments at home.

You and your healthcare practitioner can discuss the various dialysis alternatives available to you in order to determine which method of treatment will be most beneficial to you.

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About The Authors

Rian Mcconnell

Rian Mcconnell - Rian is a Villanova University graduate who was born in DuBois, Pennsylvania. He graduated from Thomas Jefferson University in Philadelphia with a medical degree. His residency was at Thomas Jefferson and its associated Wills Eye Hospital, and he finished his education with fellowships in cataract and corneal surgery at the University of Connecticut. He has a vast experience in ophthalmic surgery, with a focus on cataract surgery, corneal transplantation, and laser refractive procedures. He serves on the board of Vision Health International, an agency that provides eye care and surgery to indigent patients in Central and South America, in addition to his surgical practice.

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